Reductil 15mg

How Reductil works

Reductil 15mg buy online in USA. produces its therapeutic effects by inhibition of norepinephrine (NE), serotonin (5-hydroxytryptamine, 5-HT), and to a lesser extent, dopamine reuptake at the neuronal synapse.

By inhibiting the reuptake of these neurotransmitters, sibutramine promotes a sense of satiety and decrease in appetite, thereby reducing food intake.

Data from animal studies also suggest that sibutramine may also increase energy expenditure through thermogenic effects in both the basal and fed states, but this has not been confirmed in humans. Reductil and its major pharmacologically active metabolites (M1 and M2) do not act via release of monoamines.

Dosage

Reductil dosage

The recommendation for starting dose is 10 mg  once daily with or without food. If there is inadequate weight loss, the dose may be  after 4 weeks to a total of 15 mg once daily. The 5 mg dose should be  for patients who do not tolerate the 10 mg dose.

Blood pressure and heart rate changes should be  in account when making decisions regarding dose titration. Analysis of numerous variables has indicated that ≈ 60% of patients who lose at least 4 lbs in the first 4 weeks of treatment with a given dose of

Reductil in combination with a reduced-calorie diet lose at least 5% (placebo-subtracted) of their initial body weight by the end of 6 months to 1 year of treatment on that dose. Conversely, ≈

80% of patients who do not lose at least 4 lbs in the first 4 weeks of treatment with a given dose do not lose at least 5% (placebo-subtracted) of their initial body weight by the end of 6 months to 1 year of treatment on that dose.

If a patient has not lost at least 4 lbs in the first 4 weeks of treatment, consider reevaluation of therapy which may include increasing the dose or discontinuing Reductil.

Uses

Reductil is use in the management of obesity, including weight loss and management of weight loss. It should be use in conjunction with a caloric diet. Reductil is  for obese patients with an initial body mass index (BMI) ≥30 kg/m2 or ≥27 kg/m2 in the presence of other risk factors (e.g., hypertension, diabetes, dyslipidemia)

Precaution

Use caution when prescribing Reductil with other agents that may raise blood pressure or heart rate including certain decongestant, cough, cold and allergy medications that contain agents such as phenylpropanolamine, ephedrine or pseudoephedrine.